1. What is Resveratrol?
Resveratrol (501-36-0) is a phytoalexin and a kind of natural phenol. They are believed to function as antioxidants that protects your body against damage which can place an individual at a high risk for diseases like heart disease and cancer.
Resveratrol (501-36-0) have diverse biological activities such as antiviral, phytoestrogenic, antitumor and antioxidant. It is found in the red grape’s skin, and also in berries, and peanuts.
2. Resveratrol uses
There are many resveratrol uses which include:
- Enhancing a medical procedure known as peritoneal dialysis.
Modern research indicates that resveratrol (501-36-0) may fasten blood filtering in persons undergoing peritoneal dialysis.
- Management of PCOS (polycystic ovary syndrome)
This is a hormonal disorder which causes enlarged ovaries with cysts. Modern research indicates that resveratrol lowers testosterone in women with polycystic ovary syndrome. However, it doesn’t improve acne, unwanted hair growth, weight, or lipid levels in women with PCOS.
- Lowering Acne Severity
Research indicates that applying a gel which contains resveratrol on the face for sixty days lowers acne severity.
- Relieving RA (Rheumatoid arthritis)
Patients who take resveratrol along with medicine for Rheumatoid arthritis seems to lower the number of swollen and painful joints. Resveratrol is also believed to help reduce joint damage.
- Reducing symptoms of ulcerative colitis
Ulcerative colitis is a kind of inflammatory bowel disease. Research shows resveratrol may reduce symptoms and the activity of the inflammatory bowel disease.
- Enhancing Thinking and memory skills
Resveratrol might enhance memory and mental function in women after menopause. But, other research indicates that if resveratrol is taken for a longer time or in higher doses does not boost thinking skills or memory in healthy and old adults. Also, it may not enhance mental function in younger adults.
- Hay fever
If you use a nasal spray that contains resveratrol 3 times per day for four weeks, you will be able to lower allergy symptoms if you have seasonal allergies.
For children, using a nasal spray that contains resveratrol and beta-glucans 3 times per day for two months lowers allergy symptoms.
- Lowering (COPD) Chronic obstructive pulmonary disease
This is a lung disease which makes it harder to breathe. Research shows that taking a supplement that contains vitamin C, zinc flavonoids, and resveratrol lowers mucus production and coughing in persons with Chronic obstructive pulmonary disease.
- Management of Osteoarthritis.
Research indicates that combining resveratrol with normal treatments for knee osteoarthritis may reduce pain and improve function, stiffness more than normal treatments alone.
- Treating aging skin
To be sincere, we couldn’t exhaust the list of resveratrol uses since there are more uses that we didn’t mention here. We will however say more about resveratrol as we continue.
3. Resveratrol dosage
The following Resveratrol dosage have been studied and found to be efficient in scientific research:
Resveratrol Dosage For Adults
- For diabetes: One should take 250-1000 mg per day for up to three months.
- For seasonal allergies: One should spray two sprays of a 0.1% resveratrol spray into the two nostrils 3 times per day for up to four weeks.
4. Resveratrol benefits
Resveratrol has gained a lot of popularity for its reported disease-fighting and anti-aging powers. Some of the most known Resveratrol benefits includes:
- Affects Blood Fats Positively
Recent studies in animals have shown that resveratrol supplements might change blood fats in a healthier way.
A study conducted in 2016 fed rats with a high-polyunsaturated fat and high-protein diet and also fed them with resveratrol supplements.
The researchers discovered that the average body weight and total cholesterol levels of the rats became lower, and mice levels of “beneficial” HDL cholesterol improved.
Resveratrol supplements influences the level of cholesterol by lowering the effect of a particular enzyme which controls the production of cholesterol.
As an antioxidant, resveratrol may lower “bad” LDL cholesterol oxidation. LDL oxidation may contribute to buildup of plaque in artery walls.
In a research those who participated were fed with grape extract which had been added extra resveratrol.
After 6 months of treatment, the study showed their LDL had lowered by 4.5 percent and their oxidized LDL had declined by 20 percent in comparison to those who were given a placebo or an unenriched grape extract.
- Resveratrol Increases Insulin Sensitivity
This compound has proved to have many positive effects for diabetes, in animal studies conducted. These positive effects include preventing complications from diabetes and increasing insulin sensitivity.
Resveratrol functions by stopping a particular enzyme from transforming glucose into a sugar alcohol known as sorbitol. When too much sugar alcohol builds up in patients with diabetes, it can cause cell-damaging oxidative stress.
Below are a few more positive effects this compound may have for diabetic patients:
- Assists in lowering inflammation: This compound is believed to lower inflammation, which is a primary contributor to chronic diseases, such as diabetes.
- AMPK Activation: AMPK is a protein which assists the body breakdown glucose. Activated AMPK assists in keeping the level of the blood sugar low.
- Protection from oxidative stress: The antioxidant activity of the supplement may assist in protection against oxidative stress. This may cause some of the diabetes’ complications.
This compound may even give more positive results to persons with diabetes than people who don’t have diabetes. In one study involving animals, resveratrol and red wine were found to be more efficient antioxidants in mice with diabetes than in mice who didn’t have diabetes.
Scientific researchers say that resveratrol may be used in future in the treatment of diabetes and its associated complications, but more studies are required.
- Eases Joint Pain
Arthritis is a usual affliction that may lead to loss of mobility and joint pain.
Supplements from plants are being researched as an option to heal and protect against joint pain. If taken as a supplement, this compound might assist in protection against deteriorating of cartilage.
Breakdown of cartilage can result to the pain of joints and this is one of the major arthritis’ symptoms.
In a particular study, resveratrol was injected into the joints of the knee of rabbits with arthritis. The study found out that the injected rabbits suffered little damage to their cartilage.
Other test tube studies and animal studies has shown that resveratrol has the potential to lower inflammation and protect against joint’s damage.
- It extends the Lifespan of particular Animals
The ability of resveratrol to lengthen lifespan in a vast range of animals has become one of the major areas of resveratrol research.
There is enough evidence that resveratrol have the ability to activate certain genes which gets rid of the diseases of aging.
It functions to achieve this in a similar manner as calorie restriction, that has shown a lot of promise in extending lifespans by altering how genes express themselves positively.
It is believed that resveratrol may show a similar outcome in humans though this is not very clear. An early research studying this connection discovered that resveratrol extended lifespan in 60 percent of the animals studied.
- Prevention against Alzheimer’s disease
Resveratrol not only protects your nerve cells from damage but also fight the plaque buildup which may lead to the disease.
- Resveratrol Supplements Might Assist in Lowering Blood Pressure
Resveratrol is a promising supplement in the management of blood pressure thanks to its antioxidant properties.
A study conducted in the year 2015 found out that high doses can assist in reducing the pressure exerted on the walls of the artery when the heart beats. This kind of pressure is known as systolic blood pressure. It appears as the upper value in the readings of blood pressure.
This blood pressure usually moves up with age because of the stiffening of arteries. When too high, this becomes a heart disease risk factor.
Resveratrol lowers systolic blood pressure by helping in production of more nitric oxide. Nitric oxide causes blood vessels to relax effortlessly.
But, the authors of this study admit that more research is required before particular recommendations can be given about the correct Resveratrol dosage to maximize blood pressure management benefits.
- Resveratrol Protects the Brain Cells against damage
Early research have showed that taking resveratrol can assist in prevention of age-related cognitive. This is due to the anti-inflammatory and antioxidant activity of resveratrol.
Resveratrol interferes with protein fragments known as beta-amyloids, that forms the plaques which causes Alzheimer’s disease.
Also, this compound may bring about activities which protects brain cells against damage.
Although these findings are intriguing, scientists are still researching on how well the human body can use supplemental resveratrol in protection of brain cells. Since the research is still ongoing, that’s why it is not being used as a supplement for protection of brain cells against damage.
5. Resveratrol use to treat cancer
Multiple studies have shown that resveratrol have antitumor activities. It is therefore believed to have the capacity to treat and prevent the body against many types of cancer.
The anticancer actions of this compound have been proved in several in vivo and in vitro studies. Research have shown that this compound is able to inhibit all carcinogenesis stages such as initiation, promotion and progression.
Many research studies also suggested that this compound functions both as a chemopreventive and chemotherapeutic agent thanks to its pro-apoptosis, anti-proliferative, anti-inflammatory, and antioxidant actions.
Resveratrol is thought to target the components of intracellular signaling pathway like cell survival regulators, apoptosis, tumor angiogenic, metastatic switches and pro-inflammatory mediators, by modulating a set of transcription factors.
For example, resveratrol have shown anti-proliferative and apoptotic results on human cervical carcinoma by activating cell shrinkage in HeLa cells.
Research have shown that resveratrol demonstrated its anticancer activity in pancreatic cancer cells by lowering NAF-1 expression via stimulation of Nrf2 signaling. It also does so by activating accumulation of cellular reactive oxygen species which lead to activation of apoptosis and prevent pancreatic cancer cells proliferation.
Resveratrol also works as a Histone deacetylase inhibitor which demonstrates its antiproliferative activity by stimulating cell cycle arrest, activating autophagy and apoptosis, angiogenesis inhibition, boosting generation of reactive oxygen species causing oxidative stress, and finally mitotic cell death in cancer cells.
Resveratrol has also received immense attention as an upcoming therapeutic and preventive agent against breast cancer. This compound has also demonstrated great ability as part of combination therapy, especially in breast cancer.
Based on clinical and experimental trials, and based on molecular features of resveratrol, the compound can be used as:
- An adjuvant chemotherapy compound to prevent against metastasis after surgery and early cancer invasion;
- A neoadjuvant chemotherapy agent prior to surgery to lower tumor volume, thanks to its ability to induce apoptosis and to prevent against cancer cell proliferation
- In prevention of cancer for persons under high risk of cancer
- A chemotherapy or radiotherapy sensitization agent used in combination with chemotherapy agents such as capsaicin, docetaxel, gemcitabine, temozolomide, doxorubicin, since resveratrol may enhance their anticancer effects;
- A radioprotective agent to lower radiotherapy treatment negative effects, which include radiotherapy-induced mucositis and xerostomia.
6. Resveratrol use to treat heart disease
Resveratrol may assist in reduction of “bad” cholesterol (low-density lipoprotein (LDL) cholesterol) prevention against damage to blood vessels, and prevention against blood clots. This compound is also believed to lower the risk of inflammation. All these lowers the risk of heart disease.
Resveratrol is also believed to lower the risk of heart disease through the following activities:
- Raising the “good” cholesterol (HDL cholesterol)
- Improving the role of the cell’s layer which line your blood vessels
- Assists prevent against damage of arteries caused by high levels of LDL cholesterol
7. Resveratrol powder for sale
Resveratrol powder for sale is available as 99% Trans-Resveratrol. This form of the compound is of the highest strength and the most pure form available. Resveratrol powder for sale contains a massive 99 percent of the active ingredients. What this means is that one 500mg contains as much as 495mg Trans-Resveratrol.
8. Where to buy Resveratrol powder?
If you want to Buy Resveratrol powder, you should look for a reputable and trustworthy Resveratrol supplier online. Although there are many suppliers online, you should know that all resveratrol products are not made in a similar way by all manufacturers. Some Resveratrol powder for sale contain as little as 10 percent Trans-Resveratrol while some products don’t even indicate the amount of active ingredient which isn’t a good sign.
At buyaas.com we’re proud that our Resveratrol powder for sale is 99 percent pure meaning that it is the most pure form available in the market. We are also one of the most popular and trustworthy Resveratrol powder supplier.
- Kalantari H., Das Dipak K. Physiological effects of resveratrol. 2010;36:401–406.
- Fremont, Lucie (January 2000). “Biological Effects of Resveratrol”. Life Sciences. 66(8): 663–673.
- Keylor M.H., Matsuura B.S., Stephenson C.R.J. Chemistry and biology of resveratrol-derived natural products. Rev. 2015;115:8976–9027.